EDG-3 Rabbit Polyclonal Antibody

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Catalog Number:ABN10299
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human EDG3. AA range:115-164
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:20000-1:40000
Molecular Weight:42kDa
Purification:Affinity purification
Form:Liquid
Synonyms:S1PR3; EDG3; Sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human EDG3. AA range:115-164

Target Background

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008],function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.,

Synonyms:S1PR3; EDG3; Sphingosine 1-phosphate receptor 3; S1P receptor 3; S1P3; Endothelial differentiation G-protein coupled receptor 3; Sphingosine 1-phosphate receptor Edg-3; S1P receptor Edg-3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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