EDN1 Mouse Monoclonal Antibody

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Catalog Number:MABN82831
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG2a
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.
Reactivity:Human, Mouse
Applications:ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400
Molecular Weight:24.4KDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ET1; QME; PPET1; ARCND3; HDLCQ7

Applications

ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human EDN1 (AA: 18-212) expressed in E. Coli.

Target Background

This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Synonyms:ET1; QME; PPET1; ARCND3; HDLCQ7

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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