EEA1 Rabbit Monoclonal Antibody

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Catalog Number:MABN21570
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human EEA1
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:162kD;Observed MW:162kD
Purification:Protein A
Form:Liquid
Synonyms:EEA1;ZFYVE2;Early endosome antigen 1;Endosome-associated protein p162;Zinc finger FYVE domain-containing protein 2

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human EEA1

Target Background

Cell localization:Cytoplasm.disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate.,function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,

Synonyms:EEA1;ZFYVE2;Early endosome antigen 1;Endosome-associated protein p162;Zinc finger FYVE domain-containing protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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