Immunological Sciences

eEF2 (Phospho-Thr56) Rabbit Polyclonal Antibody

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Catalog Number:ABN05709
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized phospho derived from human eEF2 (Phospho-Thr56)
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:10000-1:20000
Molecular Weight:100kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Elongation factor 2 (EF-2)

Applications

WB 1:500-1:2000,ELISA 1:10000-1:20000

Immunogen

Synthesized phospho derived from human eEF2 (Phospho-Thr56)

Target Background

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008],function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.,PTM:Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.,PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2.,similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.,

Synonyms:Elongation factor 2 (EF-2)

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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