Immunological Sciences

EI2BG Mouse Monoclonal Antibody

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Catalog Number:MABN82933
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human EI2BG expressed in E. Coli.
Reactivity:Human
Applications:WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:200,FC 1:200-1:400
Molecular Weight:50.2kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:EIF2B3;EIF-2B; EIF2Bgamma

Applications

WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:50-1:200,FC 1:200-1:400

Immunogen

Purified recombinant fragment of human EI2BG expressed in E. Coli.

Target Background

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms:EIF2B3;EIF-2B; EIF2Bgamma

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

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