ENTPD5 Rabbit Monoclonal Antibody

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Catalog Number:MABN84556
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human ENTPD5
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,IHC 1:100-1:200,IP 1:20-1:50
Molecular Weight:Calculated MW: 48 kDa ; Observed MW: 47 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:CD39L4; Entpd5; mNTPase; NTPDase 5; PCPH; UDPase ENTPD5;;ENTPD5

Applications

WB 1:1000-1:2000,IHC 1:100-1:200,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human ENTPD5

Target Background

In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER.

Synonyms:CD39L4; Entpd5; mNTPase; NTPDase 5; PCPH; UDPase ENTPD5;;ENTPD5

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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