ERG (10X14) Rabbit Monoclonal Antibody

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Catalog Number:MABN10587
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human ERG
Reactivity:Human,Mouse
Applications:WB 1:1000-1:5000,IHC 1:100-1:200,IF-P 1:100-1:200
Molecular Weight:54kDa
Purification:Affinity purification
Form:Liquid
Synonyms:ERG;erg-3;p55;KCNH2;

Applications

WB 1:1000-1:5000,IHC 1:100-1:200,IF-P 1:100-1:200

Immunogen

A synthetic peptide of human ERG

Target Background

This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.

Synonyms:ERG;erg-3;p55;KCNH2;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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