Immunological Sciences

ERK1/2 Rabbit Monoclonal Antibody

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Catalog Number:MABN83771
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human ERK1
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW: 43,41 kDa ; Observed MW: 42,44 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, ERK-1,;ERK1/2

Applications

WB 1:1000-1:2000,ICC 1:50-1:200,FC 1:20-1:100,IP 1:20-1:50

Immunogen

A synthesized peptide derived from human ERK1

Target Background

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Synonyms:ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, ERK-1,;ERK1/2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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