ETAA1 Rabbit Monoclonal Antibody

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Catalog Number:MABN85548
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human ETAA1
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 103 kDa; Observed MW: 103 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ETAA16

Applications

WB 1:500-1:1000

Immunogen

Recombinant protein of human ETAA1

Target Background

Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717).

Synonyms:ETAA16

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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