Immunological Sciences

FADD Rabbit Polyclonal Antibody

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Catalog Number:ABN00259
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:A synthetic peptide of mouse FADD
Reactivity:Mouse
Applications:WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100
Molecular Weight:Calculated MW: 23 kDa; Observed MW: 28 kDa
Purification:Affinity Chromatography
Form:Liquid
Synonyms:FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1

Applications

WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100

Immunogen

A synthetic peptide of mouse FADD

Target Background

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Synonyms:FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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