Immunological Sciences

FAM111A Rabbit Monoclonal Antibody

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Catalog Number:MABN21235
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:Recombinant protein of human FAM111A
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:100-1:300,ICC/IF 1:100-1:300
Molecular Weight:CalcuLated MW:;Observed MW:67kD
Purification:Protein A
Form:Liquid
Synonyms:FAM111A;KIAA1895;Serine protease FAM111A;

Applications

WB 1:1000-1:5000,IHC 1:100-1:300,ICC/IF 1:100-1:300

Immunogen

Recombinant protein of human FAM111A

Target Background

Cell localization:Nucleus. Chromosome. Cytoplasm. Note=Mainly localizes to nucleus: colocalizes with PCNA on replication sites...The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Synonyms:FAM111A;KIAA1895;Serine protease FAM111A;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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