Immunological Sciences

FAM111B Rabbit Polyclonal Antibody

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Catalog Number:ABN10809
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330
Reactivity:Human,Rat,Mouse
Applications:IHC 1:100-1:200,ICC/IF 1:50-1:200,ELISA 1:5000-1:10000
Purification:Affinity purification
Form:Liquid
Synonyms:FAM111B; CANP; Protein FAM111B; Cancer-associated nucleoprotein

Applications

IHC 1:100-1:200,ICC/IF 1:50-1:200,ELISA 1:5000-1:10000

Immunogen

The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330

Target Background

This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin-like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014],sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the FAM111 family.,

Synonyms:FAM111B; CANP; Protein FAM111B; Cancer-associated nucleoprotein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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