Fas (4C3) Mouse Monoclonal Antibody

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Catalog Number:MABN03441
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG1
Clone:Monoclonal
Immunogen:A synthetic peptide of human Fas
Reactivity:Human
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 38 kDa; Observed MW: 45 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6

Applications

WB 1:500-1:1000

Immunogen

A synthetic peptide of human Fas

Target Background

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Synonyms:FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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