Immunological Sciences

Fascin Rabbit Monoclonal Antibody

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Catalog Number:MABN21011
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:Recombinant protein of human Fascin
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:54kD;Observed MW:54kD
Purification:Protein A
Form:Liquid

Applications

WB 1:1000-1:5000,IHC 1:1000-1:5000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

Recombinant protein of human Fascin

Target Background

Cell localization:Cytoplasmic.This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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