Immunological Sciences

Fascin Rabbit Monoclonal Antibody

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Catalog Number:MABN86628
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Fascin
Reactivity:Human,Mouse,Rat
Applications:WB 1:2000-1:20000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:100-1:1000,IP 1:10-1:100
Molecular Weight:Calculated MW:54 kDa; Observed MW:54 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:HSN; SNL; p55; FAN1

Applications

WB 1:2000-1:20000,IHC 1:200-1:500,ICC/IF 1:200-1:500,FC 1:100-1:1000,IP 1:10-1:100

Immunogen

Recombinant protein of human Fascin

Target Background

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Synonyms:HSN; SNL; p55; FAN1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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