Immunological Sciences

FEN1 Mouse Monoclonal Antibody

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Catalog Number:MABN85065
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:Mouse IgG1
Clone:Monoclonal
Immunogen:Purified recombinant human FEN-1 protein fragments expressed in E.coli.
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,IP 1:10-1:20
Molecular Weight:Calculated MW: 43 kDa; Observed MW: 43 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FEN1; RAD2; Flap endonuclease 1; FEN-1; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1

Applications

WB 1:500-1:1000,IP 1:10-1:20

Immunogen

Purified recombinant human FEN-1 protein fragments expressed in E.coli.

Target Background

Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

Synonyms:FEN1; RAD2; Flap endonuclease 1; FEN-1; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

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