Immunological Sciences

FGF2 Rabbit Monoclonal Antibody

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Catalog Number:MABN86980
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human FGF2
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:200-1:2000,IP 1:10-1:100
Molecular Weight:Calculated MW:31 kDa; Observed MW:19 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:BFGF; FGFB; FGF-2; HBGF-2

Applications

WB 1:1000-1:5000,IHC 1:200-1:2000,IP 1:10-1:100

Immunogen

A synthetic peptide of human FGF2

Target Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]

Synonyms:BFGF; FGFB; FGF-2; HBGF-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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