FHL2 (4I16) Rabbit Monoclonal Antibody

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Catalog Number:MABN10960
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human FHL2
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:500,IP 1:20-1:50
Molecular Weight:32kDa
Purification:Affinity purification
Form:Liquid
Synonyms:AAG11; DRAL; Fhl2; SLIM3;

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human FHL2

Target Background

May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (PubMed:28717008).

Synonyms:AAG11; DRAL; Fhl2; SLIM3;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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