Immunological Sciences

Fibroblast activation protein,alpha Rabbit Monoclonal Antibody

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Catalog Number:MABN86860
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Fibroblast activation protein,alpha
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:200
Molecular Weight:Calculated MW:88 kDa; Observed MW:97 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FAPA; SIMP; DPPIV; FAPalpha

Applications

WB 1:500-1:2000,IHC 1:100-1:200

Immunogen

Recombinant protein of human Fibroblast activation protein,alpha

Target Background

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

Synonyms:FAPA; SIMP; DPPIV; FAPalpha

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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