Immunological Sciences

Fibronectin (5H16) Rabbit Monoclonal Antibody

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Catalog Number:MABN10974
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Fibronectin
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,ICC/IF 1:200-1:500,FC 1:50-1:200
Molecular Weight:272kDa
Purification:Affinity purification
Form:Liquid
Synonyms:Anastellin; CIG; Cold-insoluble globulin; ED-B; Fibronectin; fibronectin 1; FINC; FN1; FNZ; GFND; GFND2; LETS; migration-stimulating factor; MSF;

Applications

WB 1:1000-1:5000,ICC/IF 1:200-1:500,FC 1:50-1:200

Immunogen

Recombinant protein of human Fibronectin

Target Background

FN1 Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Mostly heterodimers or multimers of alternatively spliced variants, connected by 2 disulfide bonds near the carboxyl ends; to a lesser extent homodimers. Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin (PubMed:3024962, PubMed:3900070, PubMed:3593230, PubMed:7989369). Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape (PubMed:3024962, PubMed:3900070, PubMed:3593230, PubMed:7989369). Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity). Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).

Synonyms:Anastellin; CIG; Cold-insoluble globulin; ED-B; Fibronectin; fibronectin 1; FINC; FN1; FNZ; GFND; GFND2; LETS; migration-stimulating factor; MSF;

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

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