Immunological Sciences

Fibulin 1 Rabbit Monoclonal Antibody

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Catalog Number:MABN85568
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Fibulin 1
Reactivity:Human,Mouse
Applications:WB 1:500-1:1000,IP 1:10-1:20
Molecular Weight:Calculated MW: 77 kDa; Observed MW: 77 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FBLN; FIBL1

Applications

WB 1:500-1:1000,IP 1:10-1:20

Immunogen

Recombinant protein of human Fibulin 1

Target Background

Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.

Synonyms:FBLN; FIBL1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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