FITC Anti-Human CD122/IL-2RB Antibody[TU27]

Human peripheral blood lymphocytes are stained with FITC Anti-Human CD122/IL-2RB Antibody and APC Anti-Human CD56 Antibody.

Human peripheral blood lymphocytes are stained with FITC Anti-Human CD122/IL-2RB Antibody and APC Anti-Human CD56 Antibody.

Catalog Number:MAB1151C
Conjugate:FITC
Size:100Tests
Concentration:5 μL/Test
Host:Mouse
Isotype:Mouse IgG1, κ
Clone:Monoclonal
Reactivity:Human
Applications:Each lot of this antibody is quality control tested by flow cytometric analysis. <b style="color:#0070ca">The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood).</b> Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Form:Liquid
Synonyms:IL2RB;CD122;IL15RB;P70-75;IL-2RB;Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;Interleukin-15 receptor subunit beta;p70-75 (p75)

CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.

Applications

Each lot of this antibody is quality control tested by flow cytometric analysis. <b style="color:#0070ca">The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood).</b> Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Target Background

CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.

Synonyms:IL2RB;CD122;IL15RB;P70-75;IL-2RB;Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;High affinity IL-2 receptor subunit beta;Interleukin-15 receptor subunit beta;p70-75 (p75)

Storage

This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.

Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.

Human peripheral blood lymphocytes are stained with FITC Anti-Human CD122/IL-2RB Antibody and APC Anti-Human CD56 Antibody.

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