Immunological Sciences

FLAP Rabbit Monoclonal Antibody

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Catalog Number:MABN86456
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human FLAP
Reactivity:Human
Applications:WB 1:1000-1:5000
Molecular Weight:Calculated MW:18 kDa; Observed MW:18 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:ALOX5AP; MK-886-binding protein

Applications

WB 1:1000-1:5000

Immunogen

A synthetic peptide of human FLAP

Target Background

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

Synonyms:ALOX5AP; MK-886-binding protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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