Immunological Sciences

FMO5 Rabbit Monoclonal Antibody

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Catalog Number:MABN86809
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human FMO5
Reactivity:Human,Mouse
Applications:WB 1:1000-1:5000,IHC 1:200-1:500,IP 1:50-1:100
Molecular Weight:Calculated MW:60 kDa; Observed MW:60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Dimethylaniline oxidase 5; Hepatic flavin-containing monooxygenase 5

Applications

WB 1:1000-1:5000,IHC 1:200-1:500,IP 1:50-1:100

Immunogen

A synthetic peptide of human FMO5

Target Background

Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Synonyms:Dimethylaniline oxidase 5; Hepatic flavin-containing monooxygenase 5

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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