Immunological Sciences

Foxp3 Mouse Monoclonal Antibody

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Catalog Number:MABN80527
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG
Clone:Monoclonal
Immunogen:Purified recombinant fragment of human Foxp3 expressed in E. Coli.
Reactivity:Human,Mouse
Applications:IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000
Purification:Affinity Purification
Form:Liquid
Synonyms:JM2; AIID; IPEX; PIDX; XPID; DIETER, Foxp3

Applications

IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

Purified recombinant fragment of human Foxp3 expressed in E. Coli.

Target Background

The transcription factor Foxp family includes Foxp1, Foxp2, and Foxp3. The Foxp3 (50KDa)plays a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4(+) CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.

Synonyms:JM2; AIID; IPEX; PIDX; XPID; DIETER, Foxp3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide.

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