Immunological Sciences

Frizzled 8 Rabbit Monoclonal Antibody

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Catalog Number:MABN86887
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Frizzled 8
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:200-1:500
Molecular Weight:Calculated MW:73 kDa; Observed MW:73 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FZ-8; hFZ8

Applications

WB 1:1000-1:5000,IHC 1:200-1:500

Immunogen

A synthetic peptide of human Frizzled 8

Target Background

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

Synonyms:FZ-8; hFZ8

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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