Immunological Sciences

Frzb Rabbit Monoclonal Antibody

No images available

Catalog Number:MABN87539
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of mouse Frzb
Reactivity:Mouse
Applications:WB 1:500-1:2000,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:20-1:50
Molecular Weight:Calculated MW:36 kDa; Observed MW:36 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Frp; Sfrp3; fritz; frzb-1; frezzled

Applications

WB 1:500-1:2000,ICC/IF 1:20-1:50,FC 1:20-1:50,IP 1:20-1:50

Immunogen

Recombinant protein of mouse Frzb

Target Background

Enables Wnt-protein binding activity. Involved in negative regulation of Wnt signaling pathway. Acts upstream of or within several processes, including animal organ development; negative regulation of cartilage development; and negative regulation of cell differentiation. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and skeleton. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and osteoarthritis. Orthologous to human FRZB (frizzled related protein). [provided by Alliance of Genome Resources, Apr 2022]

Synonyms:Frp; Sfrp3; fritz; frzb-1; frezzled

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

No documents available.