FTO Rabbit Monoclonal Antibody

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Catalog Number:MABN21456
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG,Kappa
Clone:Monoclonal
Immunogen:A synthetic peptide of human FTO
Reactivity:Human,Mouse,Rat,
Applications:WB 1:1000-1:5000,IHC 1:3000-1:20000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200
Molecular Weight:CalcuLated MW:58kD;Observed MW:58kD
Purification:Protein A
Form:Liquid
Synonyms:FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein

Applications

WB 1:1000-1:5000,IHC 1:3000-1:20000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200

Immunogen

A synthetic peptide of human FTO

Target Background

Cell localization:Cytoplasm, Nucleus.This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011],

Synonyms:FTO;KIAA1752;Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

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