FXN Rabbit Monoclonal Antibody

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Catalog Number:MABN87698
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human FXN
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:20-1:50,FC 1:50-1:100,IP 1:20-1:50
Molecular Weight:Calculated MW:23 kDa; Observed MW:14 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:FA; X25; CyaY; FARR; FRDA

Applications

WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:20-1:50,FC 1:50-1:100,IP 1:20-1:50

Immunogen

Recombinant protein of human FXN

Target Background

This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

Synonyms:FA; X25; CyaY; FARR; FRDA

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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