Immunological Sciences

GABAA Rα6 Rabbit Polyclonal Antibody

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Catalog Number:ABN11235
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GABRA6. AA range:61-110
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:20000-1:40000
Molecular Weight:51kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GABRA6; Gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6

Applications

WB 1:500-1:2000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human GABRA6. AA range:61-110

Target Background

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008],function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,online information:Forbidden fruit - Issue 56 of March 2005,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.,

Synonyms:GABRA6; Gamma-aminobutyric acid receptor subunit alpha-6; GABA(A) receptor subunit alpha-6

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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