Immunological Sciences

GABAA Ralpha1 Rabbit Polyclonal Antibody

Western Blot analysis of NIH-3T3, KB cells using GABAA Rα1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Western Blot analysis of NIH-3T3, KB cells using GABAA Rα1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Catalog Number:AB-J7849
Conjugate:Unconjugated
Size:100 ug
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:POLY
Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human GABRA1. AA range:61-110
Reactivity:Human;Mouse;Rat
Applications:Western Blot: 1/500 - 1/2000 Immunohoistochemistry (paraffin-embedded tissues): 1:100-1:300. ELISA: 1/10000
Molecular Weight:50kD
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form:Liquid
Synonyms:GABRA1; Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1

Applications

Western Blot: 1/500 - 1/2000 Immunohoistochemistry (paraffin-embedded tissues): 1:100-1:300. ELISA: 1/10000

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human GABRA1. AA range:61-110

Target Background

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.

Synonyms:GABRA1; Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1

Storage

Store at -20°C. Avoid repeated freeze-thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Western Blot analysis of NIH-3T3, KB cells using GABAA Rα1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100

No documents available.