Immunological Sciences

GABAA Rε Rabbit Polyclonal Antibody

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Catalog Number:ABN11240
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from the Internal region of human GABAA range: Rε.
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ELISA 1:10000-1:20000
Molecular Weight:57kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GABRE; Gamma-aminobutyric acid receptor subunit epsilon; GABA(A) receptor subunit epsilon

Applications

WB 1:500-1:2000,ELISA 1:10000-1:20000

Immunogen

Synthesized peptide derived from the Internal region of human GABAA range: Rε.

Target Background

The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein. [provided by RefSeq, Oct 2008],function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subunit:Generally pentameric. Associates with alpha and beta subunits.,tissue specificity:Expressed in many tissues. Highest levels of expression in adult heart and placenta.,

Synonyms:GABRE; Gamma-aminobutyric acid receptor subunit epsilon; GABA(A) receptor subunit epsilon

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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