Immunological Sciences

GADD45A (6C3) Mouse Monoclonal Antibody

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Catalog Number:MABN03530
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Mouse
Isotype:IgG1
Clone:Monoclonal
Reactivity:Transfected
Applications:WB 1:500-1:1000
Molecular Weight:Calculated MW: 18 kDa; Observed MW: 22 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DDIT1; GADD45

Applications

WB 1:500-1:1000

Target Background

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Synonyms:DDIT1; GADD45

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

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