Immunological Sciences

GALR1 Rabbit Polyclonal Antibody

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Catalog Number:ABN11282
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210
Reactivity:Human,Mouse
Applications:ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000
Purification:Affinity purification
Form:Liquid
Synonyms:GALR1; GALNR; GALNR1; Galanin receptor type 1; GAL1-R; GALR-1

Applications

ICC/IF 1:200-1:1000,ELISA 1:5000-1:10000

Immunogen

The antiserum was produced against synthesized peptide derived from human GALR1. AA range:161-210

Target Background

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008],function:Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated on at least one of the three cysteine residues present in the C-terminal part.,similarity:Belongs to the G-protein coupled receptor 1 family.,

Synonyms:GALR1; GALNR; GALNR1; Galanin receptor type 1; GAL1-R; GALR-1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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