Immunological Sciences

gamma Sarcoglycan Rabbit Monoclonal Antibody

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Catalog Number:MABN87210
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human gamma Sarcoglycan
Reactivity:Human,Mouse
Applications:WB 1:500-1:2000,IHC 1:200-1:500,IP 1:20-1:50
Molecular Weight:Calculated MW:32 kDa; Observed MW:32 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:A4; MAM; DMDA; SCG3; 35DAG; DAGA4; DMDA1; LGMD2C; LGMDR5; SCARMD2; gamma-SG

Applications

WB 1:500-1:2000,IHC 1:200-1:500,IP 1:20-1:50

Immunogen

Recombinant protein of human gamma Sarcoglycan

Target Background

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]

Synonyms:A4; MAM; DMDA; SCG3; 35DAG; DAGA4; DMDA1; LGMD2C; LGMDR5; SCARMD2; gamma-SG

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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