GAP-43(Mix)Mouse Monoclonal Antibody
Western blot analysis of 1） Hela, 2） 293T, 3） Mouse Brain Tissue, 4） Rat Brain Tissue using GAP-43 Monoclonal Antibody.
| Catalog Number: | MABN11295 |
| Conjugate: | Unconjugated |
| Size: | 100ul |
| Concentration: | 1mg/ml |
| Host: | Mouse |
| Isotype: | IgG |
| Immunogen: | Recombinant Protein of GAP-43 |
| Reactivity: | Human,Mouse,Rat |
| Applications: | WB 1:1000-1:2000,IHC 1:200-1:500,ICC/IF 1:50-1:200 |
| Molecular Weight: | 43kDa |
| Purification: | Affinity purification |
| Form: | liquid |
| Synonyms: | GAP43; Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46 |
The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],function:This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.,online information:Gap-43 entry,PTM:Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.,similarity:Belongs to the neuromodulin family.,similarity:Contains 1 IQ domain.,subcellular location:Cytoplasmic surface of growth cone and synaptic plasma membranes.,subunit:Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.,
Applications
WB 1:1000-1:2000,IHC 1:200-1:500,ICC/IF 1:50-1:200
Immunogen
Recombinant Protein of GAP-43
