Immunological Sciences

GATA-2 (phospho Ser401) Rabbit Polyclonal Antibody

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Catalog Number:ABN04725
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GATA2 around the phosphorylation site of Ser401. AA range:367-416
Reactivity:Human,Monkey
Applications:WB 1:500-1:2000,ELISA 1:5000-1:10000
Molecular Weight:50kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GATA2; Endothelial transcription factor GATA-2; GATA-binding protein 2

Applications

WB 1:500-1:2000,ELISA 1:5000-1:10000

Immunogen

The antiserum was produced against synthesized peptide derived from human GATA2 around the phosphorylation site of Ser401. AA range:367-416

Target Background

This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],function:Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.,sequence caution:Several sequencing errors.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Endothelial cells.,

Synonyms:GATA2; Endothelial transcription factor GATA-2; GATA-binding protein 2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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