GBA Rabbit Monoclonal Antibody

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Catalog Number:MABN86910
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human GBA
Reactivity:Human
Applications:WB 1:1000-1:5000,IHC 1:50-1:100
Molecular Weight:Calculated MW:60 kDa; Observed MW:60 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:GCB; GBA1; GLUC

Applications

WB 1:1000-1:5000,IHC 1:50-1:100

Immunogen

A synthetic peptide of human GBA

Target Background

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

Synonyms:GCB; GBA1; GLUC

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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