GCET2 Rabbit Monoclonal Antibody

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Catalog Number:MABN84513
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human GCSAM
Reactivity:Human
Applications:IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100
Molecular Weight:21 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:GCAT2; Gcet; Gcsam; hGAL; M17; M17 L;;GCSAM

Applications

IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100

Immunogen

A synthesized peptide derived from human GCSAM

Target Background

Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.

Synonyms:GCAT2; Gcet; Gcsam; hGAL; M17; M17 L;;GCSAM

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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