Immunological Sciences

GCKR Rabbit Polyclonal Antibody

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Catalog Number:ABN11350
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ELISA 1:20000-1:40000
Molecular Weight:68kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GCKR; Glucokinase regulatory protein; Glucokinase regulator

Applications

WB 1:500-1:2000,ELISA 1:20000-1:40000

Immunogen

The antiserum was produced against synthesized peptide derived from human Glucokinase Regulator. AA range:211-260

Target Background

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008],function:Inhibits glucokinase by forming an inactive complex with this enzyme.,similarity:Belongs to the GCKR family.,similarity:Contains 1 SIS domain.,tissue specificity:Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.,

Synonyms:GCKR; Glucokinase regulatory protein; Glucokinase regulator

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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