Immunological Sciences

GDF-3 Rabbit Polyclonal Antibody

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Catalog Number:ABN11384
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ELISA 1:5000-1:20000
Molecular Weight:41kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GDF3; Growth/differentiation factor 3; GDF-3

Applications

WB 1:500-1:2000,ELISA 1:5000-1:20000

Immunogen

Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

Target Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],online information:GDF3 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,

Synonyms:GDF3; Growth/differentiation factor 3; GDF-3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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