Gephyrin Rabbit Monoclonal Antibody

Western blot analysis of extracts from PC-12 cells using Gephyrin Rabbit Monoclonal Antibody at 1:1000.

Western blot analysis of extracts from PC-12 cells using Gephyrin Rabbit Monoclonal Antibody at 1:1000.

Catalog Number:MABN87803
Conjugate:Unconjugated
Size:100ul
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthetic peptide of human Gephyrin
Reactivity:Human,Mouse,Rat
Applications:WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200,FC 1:10-1:100
Molecular Weight:93 kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GPH; GEPH; HKPX1; GPHRYN; MOCODC

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]

Applications

WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200,FC 1:10-1:100

Immunogen

A synthetic peptide of human Gephyrin

Target Background

This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]

Synonyms:GPH; GEPH; HKPX1; GPHRYN; MOCODC

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.

Western blot analysis of extracts from PC-12 cells using Gephyrin Rabbit Monoclonal Antibody at 1:1000.

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