Immunological Sciences

GHRH-R Rabbit Polyclonal Antibody

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Catalog Number:ABN11439
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GHRHR. AA range:351-400
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000
Molecular Weight:47kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GHRHR; Growth hormone-releasing hormone receptor; GHRH receptor; Growth hormone-releasing factor receptor; GRF receptor; GRFR

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human GHRHR. AA range:351-400

Target Background

This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq, Jun 2010],disease:Defects in GHRHR are a cause of isolated growth hormone deficiency type IB (IGHD IB) [MIM:262400]; also known as pituitary dwarfism I. IGHD IB is an autosomal recessive deficiency of GH which cause short stature.,function:Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.,similarity:Belongs to the G-protein coupled receptor 2 family.,tissue specificity:Pituitary gland.,

Synonyms:GHRHR; Growth hormone-releasing hormone receptor; GHRH receptor; Growth hormone-releasing factor receptor; GRF receptor; GRFR

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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