GLI3 Rabbit Polyclonal Antibody
Immunofluorescence analysis of HepG2 cells, using GLI-3 Antibody. The picture on the right is blocked with the synthesized peptide.
| Catalog Number: | ABE5561 |
| Conjugate: | Unconjugated |
| Size: | 100ug |
| Concentration: | 1mg/ml |
| Host: | Rabbit |
| Isotype: | IgG |
| Clone: | POLY |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human GLI-3. AA range:11-60 |
| Reactivity: | Hu,Ms, Rt |
| Applications: | IHC, IF |
| Molecular Weight: | 14kDa |
| Purification: | Affinity Purified |
| Form: | Liquid |
| Synonyms: | GLI3; Transcriptional activator GLI3; GLI3 formof 190 kDa; GLI3-190; GLI3 full length protein; GLI3FL |
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008],
Applications
IHC, IF
Immunogen
The antiserum was produced against synthesized peptide derived from human GLI-3. AA range:11-60
