Immunological Sciences

Glutaminase Rabbit Monoclonal Antibody

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Catalog Number:MABN85616
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human Glutaminase C
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20
Molecular Weight:Calculated MW: 73 kDa; Observed MW: 68 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:Glutaminase kidney isoform; GLS; GLS1; KGA; K-glutaminase; GAM; GAC; Glutaminase C; L-glutamine amidohydrolase

Applications

WB 1:500-1:1000,ICC 1:50-1:200,IP 1:10-1:20

Immunogen

Recombinant protein of human Glutaminase C

Target Background

Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers.

Synonyms:Glutaminase kidney isoform; GLS; GLS1; KGA; K-glutaminase; GAM; GAC; Glutaminase C; L-glutamine amidohydrolase

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

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