Immunological Sciences

GNE Rabbit Monoclonal Antibody

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Catalog Number:MABN84047
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:A synthesized peptide derived from human GNE
Reactivity:Human
Applications:WB 1:1000-1:2000,ICC 1:50-1:200
Molecular Weight:Calculated MW: 79 kDa ; Observed MW: 75 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:DMRV; GNE; IBM2; ManAc kinase; Uae1;;GNE

Applications

WB 1:1000-1:2000,ICC 1:50-1:200

Immunogen

A synthesized peptide derived from human GNE

Target Background

Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation.

Synonyms:DMRV; GNE; IBM2; ManAc kinase; Uae1;;GNE

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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