GPNMB Rabbit Monoclonal Antibody

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Catalog Number:MABN87543
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Monoclonal
Immunogen:Recombinant protein of human GPNMB
Reactivity:Human
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:500,FC 1:200-1:500
Molecular Weight:Calculated MW:64 kDa; Observed MW:95,120 kDa
Purification:Affinity Purification
Form:Liquid
Synonyms:NMB; HGFIN; PLCA3

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:500,FC 1:200-1:500

Immunogen

Recombinant protein of human GPNMB

Target Background

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms:NMB; HGFIN; PLCA3

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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