Immunological Sciences

GPR119 Rabbit Polyclonal Antibody

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Catalog Number:ABN11630
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GPR119. AA range:186-235
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000
Molecular Weight:37kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GPR119; Glucose-dependent insulinotropic receptor; G-protein coupled receptor 119

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:5000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR119. AA range:186-235

Target Background

This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.[provided by RefSeq, Jan 2010],function:Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Predominantly expressed in the pancreas, especially in the islets.,

Synonyms:GPR119; Glucose-dependent insulinotropic receptor; G-protein coupled receptor 119

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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