Immunological Sciences

GPR56 Rabbit Polyclonal Antibody

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Catalog Number:ABN11692
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GPR56. AA range:251-300
Reactivity:Human,Rat,Mouse
Applications:WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000
Molecular Weight:78kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GPR56; TM7LN4; TM7XN1; G-protein coupled receptor 56; Protein TM7XN1

Applications

WB 1:500-1:2000,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR56. AA range:251-300

Target Background

This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],disease:Defects in GPR56 are the cause of bilateral frontoparietal polymicrogyria (BFPP) [MIM:606854]. BFPP is characterized by disorganized cortical lamination that is most severe in frontal cortex.,function:Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,tissue specificity:Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.,

Synonyms:GPR56; TM7LN4; TM7XN1; G-protein coupled receptor 56; Protein TM7XN1

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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