Immunological Sciences

Granzyme K Rabbit Polyclonal Antibody

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Catalog Number:ABN11743
Conjugate:Unconjugated
Size:100μL
Concentration:1mg/ml
Host:Rabbit
Isotype:IgG
Clone:Polyclonal
Immunogen:The antiserum was produced against synthesized peptide derived from human GRAK. AA range:61-110
Reactivity:Human,Mouse,Rat
Applications:WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000
Molecular Weight:33kDa
Purification:Affinity purification
Form:Liquid
Synonyms:GZMK; TRYP2; Granzyme K; Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2

Applications

WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:10000-1:20000

Immunogen

The antiserum was produced against synthesized peptide derived from human GRAK. AA range:61-110

Target Background

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008],similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in lung, spleen, thymus and peripheral blood leukocytes.,

Synonyms:GZMK; TRYP2; Granzyme K; Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2

Storage

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

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